There was a problem with PHD2 and the ASI cameras due to the ASCOM driver, but that is now fixed (just update). They work fine together.
I think MetaGuide is overall an excellent guiding package, in some ways better suited to CMOS guiders that can do fast frames, due to its use of centroid averaging. BUT (and it was a big but for me), it didn't integrate with my particular capture software for dithering, so I typically use PHD2.
PHD2 has simply the best drift alignment tool out there too.
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